O32: TRANSPARENCY IN SURGICAL RANDOMISED CONTROLLED TRIALS: CROSS-SECTIONAL, OBSERVATIONAL STUDY

Abstract Introduction Randomised controlled trials (RCT) often provide the scientific basis on which commissioning and treatment decisions are made. It is essential that their results methods reported transparently. The aim of this study was to explore transparency with respect trial registration, disclosure funding sources, conflicts interest (COI), data sharing. Method This a cross-sectional review surgical RCTs. Data were extracted from RCTs in ten high-impact journals published years 2009, 2012, 2015, 2018. Outcomes incidence investigator COI, presence statement sharing plans. Result A total 475 eligible for analysis. Trial registration present 73 (67%) studies 137 (84%) 111 (89%) 2015 110 (93%) Funding statements provided 55%, 65%, 69.4%, 75.4% manuscripts, respectively. Conflicts 49.5%, 89.1%, 94.6%, 98.3% only 15 (3.2%) Eleven these most recently Conclusion statements, personal have improved rapidly over last 10 years. In contrast, plans exceptionally low. may contribute research waste represents an target improvement. Take-home message